PRP vs PRF for Hair Loss – Which Is Better?

PRF hair treatment in progress for hair thinning at a Fayetteville, GA medical aesthetics clinic

If you’re noticing thinning hair, a widening part, or hair that just doesn’t feel as full as it used to, you’re not alone—and you’re not without options. At Essentia Women’s Health & Aesthetics in Fayetteville, GA, we specialize in regenerative hair therapies like Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF). But with both options available, many clients ask: What’s the difference between PRP vs PRF for hair loss—and which one is better?

In this article, we’ll break it down so you can make a confident, informed decision about your next step toward fuller, healthier hair.

Key Differences Between PRP and PRF

PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin) both come from your own blood and use growth factors to stimulate healing and regeneration. But the way they’re processed—and how they work—differs.

Feature PRP PRF
Centrifuge Speed Higher speed  Lower speed
Anticoagulants Added None
Cell Content Platelets only Platelets, white blood cells and stem cells
Release of Growth Factors Immediate Slow, over time
Consistency Liquid Gel-like fibrin matrix

The bottom line? PRF is considered more “biologically active” because it holds more regenerative cells and releases growth factors over a longer period.

How PRP Stimulates Hair Follicles

PRP is one of the most well-studied and widely used treatments for hair loss. It works by:

  • Increasing blood supply to the hair follicle
  • Extending the hair growth cycle
  • Stimulating collagen and tissue remodeling

After drawing a small amount of your blood, we spin it in a centrifuge to separate the platelets. Then we inject the concentrated plasma into areas of thinning. This jump-starts healing at the follicular level, helping to thicken hair and reduce shedding.

PRP is a great option for clients with early-stage hair loss, postpartum shedding, or general thinning who want to maintain their current hair density and stimulate regrowth.

What Makes PRF Different (and Potentially More Powerful)

PRF goes one step further. By spinning the blood at a lower speed and without anticoagulants, we preserve more white blood cells, fibrin, and stem cells. This creates a natural scaffolding that allows growth factors to be released gradually—usually over 7 to 10 days.

What does that mean for you?

  • Longer-lasting stimulation of the hair follicle
  • Enhanced tissue healing
  • A more holistic, slow-release approach

PRF is especially helpful for clients with more advanced thinning or hair that’s been resistant to other treatments. It’s also ideal if you want a fully natural option with no additives.

PRP vs PRF for Hair Loss: Which Is Better?

Both treatments are effective, but here’s how to think about it:

  • Choose PRP if you want immediate stimulation, are early in your hair loss journey, or are prepping for a big event (yes, it’s a great pre-photo glow-up for your scalp).
  • Choose PRF if you want longer-lasting benefits, have more stubborn thinning, or want to boost results from past PRP treatments. 

At Essentia, we offer both PRP and PRF because we understand that your hair story is personal—and your treatment should be too. We’ll help you choose the right option based on your goals, hair health, and timeline.

Treatment Frequency and Recovery

Whether you choose PRP or PRF, here’s what the treatment process typically looks like:

  • Initial sessions: 3 to 4, spaced 4–6 weeks apart
  • Maintenance: 1–2 times per year
  • Downtime: Minimal; most clients resume normal activities within 24 hours 

We also provide a take-home scalp care kit and guidance for stimulating your follicles between sessions, because what you do outside the office matters just as much as what we do in it.

FAQs About PRP vs PRF for Hair Loss

Q: What’s the difference between PRP and PRF for hair loss?
A: PRP is spun at higher speeds and contains primarily platelets. PRF is spun slower and includes white blood cells, fibrin, and stem cells for longer-term regeneration.

Q: Which one provides better results for thinning hair?
A: It depends on your stage of hair loss. PRF may offer more sustained benefits, especially for advanced thinning.

Q: How many sessions are needed for PRP vs. PRF?
A: Both require 3–4 sessions initially, followed by maintenance 1–2 times a year.

Q: Is PRF more natural or effective than PRP?
A: PRF is 100% natural with no additives, and it may be more effective for long-term results due to the slow-release growth factors.

Q: Can I switch between PRP and PRF treatments?
A: Yes! Some clients start with PRP and transition to PRF over time. We’ll guide you based on your response and goals.

Key Takeaways

  • PRP and PRF both use your blood to stimulate hair growth but differ in how they’re processed and how growth factors are released.
  • PRP offers quicker activation; PRF provides slower, more sustained regeneration.
  • PRF includes stem cells and fibrin, making it potentially more powerful for long-term improvement.
  • Both require multiple sessions and maintenance, with minimal downtime.
  • Essentia in Fayetteville offers both options and a personalized approach to help you reclaim your healthiest hair.

Not sure which is right for you? Let’s talk.
Book a consultation at essentiaintima.com to discuss your goals and let our team guide you toward the most effective treatment for your hair loss.

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